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W.E.B. DuBois life and role in the history of education Essay

W.E.B. DuBois life and job throughout the entire existence of training - Essay Example William Edward Burghardt Du Bois was a persuasive ...

Friday, January 31, 2020

SOC 111 LS1 Essay Example | Topics and Well Written Essays - 500 words

SOC 111 LS1 - Essay Example   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   There was an individual who was a very close business associate with my father who I will identify as Mr. X. For reasons unbeknownst to me, Mr. X was as excellent sales associate and had a very successful professional career; however it is the case that this individual had a very task oriented/problem solving orientation when it came to personal matters. I knew Mr. X personally and (Successful as he may be) had a lot of difficulties in his social life and in general terms he was not a pleasant person to be around in social circumstances. Despite these problems Mr. X had been happily married until his wife suffered a brain aneurysm and passed away quite suddenly. Newly widowed, Mr. X had a great deal of difficulty in dealing with his grief and began to see much of his personal life spiraling out of control. As it is the case that most issues in Mr. X’s professional life were viewed as being a task oriented it could be the case that h e looked at his grief as a problem that he was trying to solve. It comes as no surprise that there was no solution to Mr. X’s Grief, and it was the case that he started to see his professional life start to decline as well, and around this time Mr. X was began battling with problematic drinking. On the advice of his work colleagues (Including my father), Mr. X started seeing a therapist. As I highlighted earlier, Mr. X always had a task oriented personality and by being active in his routines (Typically work routines) Mr. X on a personal level was in general terms happier. Mr.X was simply unable to handle the problem of his grief, and by failing in this aspect of his life it started to negatively affect other parts of his life and he was on track to seeing his life spiral out of control. The advice of the therapist was to simply not view his grief as some sort of failure on his behalf and from a stregnths based perspective his

Thursday, January 23, 2020

A Tale of Two Hearts in Charlotte Brontes Jane Eyre :: Jane Eyre Essays

A TALE OF TWO HEARTS While an artist uses a variety of colors and brushes to create a portrait, Charlotte Bronte used contrasting characters and their vivid personalities to create a masterpiece of her own.   In her novel Jane Eyre, Bronte uses narration and her characters to portray the struggle between a society’s Victorian realism and the people’s repressed urges of Romanticism.   In order to discern between the Victorian and Romantic themes, Bronte selects certain characters to portray the perfect stereotype of each theme.   Mademoiselle Celine Varens is the model of the Romantic attitude.   Varens a â€Å"French opera-dancer† found herself as the â€Å"grande passion† of Mr. Rochester.   The amour between Rochester and Varens started in a â€Å"complete establishment of servants, a carriage, cashmere, diamonds, dentells, etc.† and ended with Rochester â€Å"finding her out† with another man.   Varens’ irrationality did not only affect Rochester, but also her child: â€Å"she abandoned her child and ran away with a musician or singer.†Ã‚   Celine Varens, a woman in a daring profession, led a life of passion, freedom and irresponsibility.   Her life was ballad of adventure idolized by Romantics but frowned upon by society.   Mrs. Reed is the perfect representative of Victorian realism.   She had all t he visual attributes found in a Victorian styled lady.   She possessed gentry as the mistress of Gateshead Hall and her material wealth was made obvious by the luxuries found in her home –â€Å"a bed supported on massive pillows of mahogany, hung with curtains of damask†Ã¢â‚¬â€and in her children â€Å"in their Muslim frocks and scarlet sashes.†Ã‚   Besides wealth and gentility, Mrs. Reed also maintained Victorian characteristics of insularity and censoriousness.   Ã¢â‚¬Å"Eliza, John and Georgiana were now clustered round their mama in the drawing room: she lay reclined on the sofa by the fireplace and her darlings about her†¦Ã¢â‚¬  Mrs. Reed literally maintains insularity – snobbishly creating an island of her and her children, detaching themselves from Jane.   Lastly Mrs. Reed exercised censoriousness towards Jane on a continual basis until Jane was left with â€Å"a habitual mood of humiliation, self doubt, forlorn depression.†Ã‚   Jane’s state is the result of the Victorian need of moral severity, which was expressed by blame and disapproval.   Bronte uses Varens and Reed to paint the contrast between the Romantics controlled by emotion, freedom and imagination and the Victorians who exhibit middle-class stuffiness and pompous conservatism. But any author can capture the essence of two societies and illustrate the opposites in two opposing characters.

Wednesday, January 15, 2020

Social Smoking

One potentially important factor is social influence (Van den Putte, Yzer, & Brunsting, 2005), as this has been shown to be a significant predictor of the uptake of smoking (Kobus, 2003; Mayhem, Flay, & Mott, 2000). An important model which explicitly takes into account social influence and the role of the social environment is the theory of planned behaviour (TPB; Ajzen, 1991). This theory proposes that people’s intentions to behave in particular ways are informed by three main factors: their personal attitude towards the behaviour; their perceptions of social pressure from significant others to perform the behaviour, or subjective norms; and the amount of control they believe they have over performing the behaviour, or perceived behavioural control. In the smoking domain, TPB variables have been shown to predict both quitting intentions (Abrams & Biener, 1992; Droomers, Schrijvers, & Mackenbach, 2004; Godin, Valois, Lepage, & Desharnais, 1992; Norman, Conner, & Bell, 1999) and actual quitting (Godin et al. , 1992; Norman et al. , 1999), as well as the uptake of smoking among adolescents (Wilkinson & Abraham, 2004). Of primary interest to the present study is the role of subjective norms. Out of the three main TPB variables, norms have generally been shown to have the weakest effect on intentions (Armitage & Conner, 2001; Godin & Kok, 1996). However, it has been argued that this is due to the poor measurement and inconsistent conceptualisation of norms (Armitage & Conner, 2001) or the lack of variation of norms within a culture at any point in time. Research by Wiium, Torsheim, and Wold (2006) demonstrated that different kinds of norms differentially influence intentions and behaviour, and argued that the assessment of different kinds of norms in the TPB model can both extend the concept of ‘norm’ and improve its predictive power. In the present study we distinguish between norms from significant others (i. e. erceptions of what significant others believe about smoking) and societal norms (i. e. perceptions of what society in general believes about smoking). In this respect, we depart from previous smoking research that has treated these kinds of norms as two components of a higher order social norm (e. g. Hammond, Fong, Zanna, Thrasher, & Borland, 2006). We argue that it is important to distinguish between these two sources of normative influence, as individuals’ perceptions of the broader social desirability of smoking may differ from their perceptions of what their significant others believe. This distinction is particularly important when examining cultures that have quite different normative environments regarding smoking. In some countries, such as Australia and the USA, smoking has become a socially undesirable behaviour. This has occurred, at least partially, through decades of communication about the harms of smoking and a range of tobacco control policies, including the reduced capacity of tobacco companies to promote their products, health warnings on cigarette packs, and restrictions on where smoking is permitted. However, the social undesirability of smoking is not a global phenomenon. Some countries, such as Malaysia, have had a comparatively tobacco-friendly environment, with a relative lack of strongly enforced tobacco control policies and a higher prevalence of smoking than in many Western countries, at least among men. Nevertheless, individual Malaysian smokers’ families and close social networks may still disapprove of smoking. Thus, it is of interest to examine the relative influence of these two potentially opposing smoking norms on quitting intentions in different countries.

Tuesday, January 7, 2020

Gun Control And The United States - 957 Words

One of the most debated topics in the world today is the conflicting belief on whether people should or should not own and use guns. Gun control is generally defined as â€Å"laws or policies that regulate the manufacture, sale, transfer, possession, modification, or use of firearms† (Gopink, 2012). The views and opinions of this situation vary across the world. Some territories set strict rules and difficult procedures to obtain weapons while others allow easy access. People are usually very opinionated about this subject, causing debates and conflicting reactions. Gun control is one of the most controversial topics with numerous approaches to how it should be handled. The United States alone has â€Å"88.8 guns per 100 people, or about 270,000,000 guns† (Cornell, 2015). This is the highest total number of guns per country in the entire world. 22 percent of Americans â€Å"own one or more gun† (Cornell, 2015). These statistics are overwhelming to some people, w hile others see it as completely normal, or even excellent. Many laws have been passed to regulate this procedure, and citizens often cast their vote for officials solely based off of their opinion on gun control and the way weapons should be handled. All in all, the statistics are debated due to the fact that no one can agree on this questionable matter. One of the leading viewpoints on gun control is that citizens of the United States should give up their guns and that only military should be given the privilege of operating aShow MoreRelatedGun Control Of The United States1698 Words   |  7 Pagesshootings that has happened throughout the Unites States has created a great divide among Americans on what should our nation do to prevent further shootings from happening. Many people believe that forcing new laws on how people purchase weapons should require background checks. Gun Control in the United States of America is a topic that has had lots of criticism and support by many c itizens. The critical people of this topic believe that the guns do not kill people, it is the people that kill peopleRead MoreGun Control And The United States1569 Words   |  7 PagesIn the United States gun control is a big controversy that has been blown out of proportion the last few years. Anything that has to do with guns in the news, reporters say it is the guns fault. Gun control laws are being changed and morphed for the new society that we live in today. What gun control really means is a group of laws to control the selling and use of guns.(1). Statistics have proven that most people want more control on guns. Many surveys have shown that the benefits of gun controlRead MoreGun Control Of The United States Essay1412 Words   |  6 PagesGun Control Proposal Gun control is a highly controversial topic in the United States. There are many people who are for gun control - people who want to have stricter laws to make it so criminals and other dangerous people can’t obtain a firearm. But, there are also the people who disagree with gun control laws and believe there should be a more lenient gun control to help people defend themselves during risky situations. Many gun control laws have been passed for many years. While many have beenRead MoreGun Control And The United States929 Words   |  4 PagesGun control has been a debated, revisited and revised issue for more than a century in the United States. Recently, after several mass shootings in the United States, gun violence issues are; yet again, renewed and in the forefront for the United States. This paper will consist of insight on gun violence in the United States and the newly imposed gun control policies by President Obama; along with, the arguments for and against the new policies and what roles both the formal and informal actorsRead MoreGun Control Of The United States1166 Words   |  5 PagesSince America’s birth, guns have played a large part in it’s society. Citizens of the United States have used firearms to protect the land they love, and their families. They even use them for engaging activities such as hunting and sport. Though firearms may seem to have a commonplace in society, weighing the rights and liberties of citizens against the safety and welfare of the public has always been a delicate process. In the United States, gun control is a of heated issue that has two sides.Read MoreGun Control And The United States988 Words   |  4 PagesGun Control Reassessment in the United States Imagine this: you are in World History class at your high school almost falling asleep learning about Ancient China. It is a normal day for you and your classmates, until you hear an announcement from the principal. You expect the typical lockdown drill, but this situation is far from typical. A man with a gun breaks into your school. BANG! Several of your classmates are killed before this man can be controlled. You survive, but live the rest of yourRead MoreGun Control And The United States1435 Words   |  6 PagesGun Control For gun control, there should be some requirements for the people to take in order to own a gun for themselves. Throughout the United States, gun control should allow people to still have guns; however, the citizens should go through some changes to ensure safety throughout the nation. Gun control has given some helpful ideals before that would help the people understand the responsibilities of their guns. They want to make sure that these laws maintain to progress as a better solutionRead MoreGun Control Of The United States1704 Words   |  7 Pagesshootings that has happened all through the Unites States has made an great divide among Americans on what ought our country do to keep further shootings from happening. Numerous individuals trust that forcing new laws on how people buy weapons should require background verifications. Gun Control in the United States of America is a topic that has had lots of criticism and support by numerous citizens. The critical people of this topic trust that the guns don t murder people, is that people kill peopleRead MoreGun Control in the United States1306 Words   |  6 Pages Gun Control in the United States has gone out of control. The United States should enforce laws to not allow any guns in a house hold in order to reduce violence and crime in the country. Reducing the rate of crime in the United States, controlling big weapons, taxing ammunition, and gun collection can help make this happen. Gun Control can make this country a safer environment to live in. Gun Control has obviously gone out of control in the recent years. Look around, they are everywhere. ReducingRead MoreGun Control Of The United States853 Words   |  4 Pagesbut also criminal sphere. Crime in the United States remains one of the main problems of the country. Every year, 6 million Americans become a victims of crime, murders occur every 24 minutes, rape occur every 5 minutes, robbery occur every 54 seconds. Life becomes dangerous and we need to be able to protect your family by yourself, your business, your property. Therefore so many people thinking about to buys guns and to have guns at home. In addition, the gun is freedom. We live in a free country

Monday, December 30, 2019

A Few Good Men Analysis - 1331 Words

A Few Good Men Analysis Philip G. Zimbardo, Herbert C. Kelman and V. Lee Hamilton, and Crispin Sartwell directly or implicitly discuss the power of situation. Stanford professor Zimbardo’s â€Å"The Stanford Prison Experiment,† analyzes and explains his experiment, in which twenty-one male Stanford students were assigned roles as guards and prisoners in a simulated prison. He summarizes the extreme behavior and reactions that resulted in early termination of the experiment, and discusses the power of situational factors in altering the subject’s expected behavior (Zimbardo 116-117). Similarly, in â€Å"The My Lai Massacre,† Herbert C. Kelman and V. Lee Hamilton summarize this atrocious crime committed by the U.S. military; furthermore, they†¦show more content†¦Dr. Phil interviews a military Ranger, Alex, who robbed a bank inadvertently. The Ranger was under the impression that he was taking place in a military drill, as his superior ordered a â⠂¬Å"hit† on the bank. Alex, like Dawson, received orders from a commanding officer to carry out an act he would not perform on his own accord. Alex claimed he felt as though â€Å"something was off,† but he completed the robbery anyway, because he was ordered to (â€Å"When Good People do Bad Things†). Zimbardo would attribute Alex’s actions to the situational force of the military training he was under; similarly, he would credit Dawson’s actions to a deep respect for the military code: â€Å"unit, corps, God, country.† Suicide checks, in which a solider puts a gun to his/her head and pulls the trigger, not knowing whether it is loaded or not, provide an example of the extreme dictation of the military code over soldiers (â€Å"When Good People do Bad Things†). This example effectively provides reasoning to why Dawson repetitively stresses that his actions were not wrong, and he will not disrespect the code by agreeing to Kaffee and R oss’ bargain that would allow him to go home in six months. If true, this helps explain how terrorists are willing to commit depraved actions, because it furthers a cause they deem more important than their crime. Kelman and Hamilton logically utilize Zimbardo’s concept of situational forces andShow MoreRelatedAnalysis Of A Few Good Men1647 Words   |  7 PagesBreaking the Chains of Social Conformity â€Å"You can’t handle the truth!† In the movie A Few Good Men, directed by Rob Reiner and based off a true story, that is an iconic quote. Although this movie was made in the early 1990s, this can be quoted by many people today. However, many do not know the significance of this phrase. It seems pretty straightforward, but it contains a deeper meaning than what the surface level may reveal. Throughout the movie, it investigates a case where they are trying toRead MoreA Few Good Men Legal Analysis796 Words   |  4 PagesA Few Good Men Legal Analysis - Aakriti Gera A Few Good Men is a 1992 American legal drama directed by Rob Reiner. The story follows the court-martial of two U.S. Marines, who are charged with the murder of a fellow marine and the problems faced by the lawyers, of the accused, while preparing their defenses. The Marines are on a murder trial for carrying out a â€Å"code red† order. The movie refers to â€Å"code red† as a type of extrajudicial punishment used for an alleged crime or offense, which is carriedRead MoreA few good men case analysis1494 Words   |  6 Pagesthe judge thunder objections, but Jessup is caught in an awkward situation: he had stated that Santiago was due to be transferred off the base for his own safety in case the other Marines sought retribution, but also stated that Marines are honorable men who always follow orders - thus Kaffee argues that if the other Marines were ordered to leave Santiago alone and always follow orders, then Santiago would have been in no danger whatsoever and th us Jessup s argument that he was to be transferred forRead MoreAnalysis Of The Movie A Few Good Men Essay1555 Words   |  7 PagesConsequences of Obedience Late one night, two Marines, Lance Corporal Harold Dawson and Private First Class Louden Downey carried out a â€Å"code red† on Private First Class William Santiago that ultimately resulted in Santiago’s death. In the film A Few Good Men, nominated for an Academy Award for best picture and directed by Rob Reiner, Lieutenant Daniel Kaffee, investigates the crime and develops his own opinion on whether the murder of Santiago was ethically stable in terms of Dawson and Downey’s mentalRead MoreAnalysis Of The Film A Few Good Men 1166 Words   |  5 Pagesreason out whether a decision is either wrong or right using their conscience, their ability to create relationships that can hold a similar value to that of biological relationships, and despite having a capacity for sin, humans are still good. In the film A Few Good Men, three lawyers are left with a case, where two Marines on Guantanamo Bay have been convicted of murdering a fellow comrade. This film clearly sh owed as to what it means to be human. Through the film, the audience was shown that the relationshipsRead MoreMovie Analysis : A Few Good Men 2258 Words   |  10 PagesThe hit film â€Å"A Few Good Men† which stars Tom Cruise as Lt. Daniel Kaffe, Demi Moore, as Lt. Cdr. JoAnne Galloway and Jack Nicholson as Col. Nathan R. Jessep, gives us an in-depth look on a major role in our criminal justice system. The film depicts the events and steps that are taken leading into the trial, as well as inside the courtroom of our criminal justice system. I got the film from a friend who had it on DVD at his house and he allowed me to borrow it for the assignment. Throughout the movieRead MoreComparative Analysis a Few Good Men Essay1591 Words   |  7 PagesComparative Analysis: A Few Good Men â€Å"You dont need a patch on your arm to have honor.† Lt. Daniel Kaffee, portrayed by Tom Cruise, says at the end of the movie to Lance Cpl. Dawson after the final ruling is read, stating PFC. Downy and Lance Cpl. Dawson are innocent but are dishonorably discharged from the military. A Few Good Men portrays the negative impact on military personally from strict obedience. Lt. Daniel Kaffee, along with Lt. Cdr. JoAnne Galloway and Lt. Sam Weinberg; played byRead MoreEssay on Comparative Analysis of A Few Good Men1371 Words   |  6 PagesThe motion picture A Few Good Men challenges the question of why Marines obey their superiors’ orders without hesitation. The film illustrates a story about two Marines, Lance Corporal Harold W. Dawson and Private First Class Louden Downey charged for the murder of Private First Class William T. Santiago. Lieutenant Daniel Kaffee, who is known to be lackadaisical and originally considers offering a plea bargain in order to curtail Da wson’s and Downey’s sentence, finds himself fighting for the freedomRead MoreEssay on A Few Good Men Clip Analysis 1143 Words   |  5 Pagesactors, backdrops, costumes, props and lighting used to meet the director’s vision (Goodykoontz Jacobs, 2011, Sec 3.2). This paper will discuss the elements of a movie clip entitled â€Å"You Can’t Handle the Truth† from the movie A Few Good Men. The movie, A Few Good Men, was released in 1992. It was a box office success grossing over $237 million globally. The story was about two marines on trial for killing a squad member. Tom Cruise and Demi Moore both starred in the movie as Marine DefenseRead MoreAnalysis Of Columbia Pictures A Few Good Men 1955 Words   |  8 Pages The following work aims to take a closer look at cultures, leadership and paradigms in Columbia Pictures’ (1992) film; A Few Good Men. This film provides many examples of differing cultures as well as illustrating examples of leadership, management, and followership. Many lessons can be learned; standing up for what is right and standing up for what you believe in are apparent, as well as leaders not always making the best decisions. At the end of the day, one must be at peace with the direction

Sunday, December 22, 2019

The Role Of Women Throughout Society A Pacifist Vs. A...

Essay Number One: The Role of Women in society : A Pacifist vs. A Feminist Do you remember those word problems in math class that were about two people leaving two different points and ending up at the same place? This is like how Mary Wollstonecraft and Anna Letitia Barbauld went about the role of women within society. Anna Letitia Barbauld could be classified as a pacifist that believed in peace and peace for both sexes. While Mary Wollstonecraft could be categorized as a feminist, that had strong opinions about how women should be equal. Both authors desired the same destination, just took different routes. The difference and similarities between Mary Wollstonecraft and Anna Letitia Barbauld’s opinion of women’s rights. Anna†¦show more content†¦Anna Barbauld seemed to believe that Mary Wollstonecraft’s opinion in sighted conflict rather than the peace. Anna Letitia Barbauld stated â€Å"Make treacherous man thy subject, not thy friend, thou many command, but canst be free† Mary Wollstonecraft was born on April 27th, 1759, in Spitalfields, London, England. Mary Wollstonecraft is known for her strong opinion on the standings of women’s rights. In today’s media, she would and should be classified as a feminist. Within a vindication of rights of woman, Wollstonecraft calls for the equality of men and women in certain areas of life. Wollstonecraft first states that â€Å"but I see not the shadow of a reason to conclude that their virtue should differ in respect to their nature (Wollstonecraft)†. Mary Wollstonecraft is stating that she does not feel that the nature or masculine strength of a man should be superior. Just because men are stronger does not mean they are better than women. As well as women being better because they are sensitive and in touch with their feelings. This is a very basic and standard concept of feminism, even today. Wollstonecraft also appeals to men to join the feminist movement. â€Å"I appeal to their unders tandings; as a fellow creature, claim in the name of my sex, some interest in their hearts; I entreat them to assist to emancipate their companion. This goes back to the overall belief that feminism is not radical andShow MoreRelatedOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 PagesUnnatural Acts: Charting the Future of Teaching the Past Sharon Hartman Strom, Political Woman: Florence Luscomb and the Legacy of Radical Reform Michael Adas, ed., Agricultural and Pastoral Societies in Ancient and Classical History Jack Metzgar, Striking Steel: Solidarity Remembered Janis Appier, Policing Women: The Sexual Politics of Law Enforcement and the LAPD Allen Hunter, ed., Rethinking the Cold War Eric Foner, ed., The New American History. Revised and Expanded Edition E SSAYS ON Read MoreSAT Top 30 Essay Evidence18536 Words   |  75 Pagesdisappearance is still a lively and controversial topic of debate. Amelia Earhart left behind a legacy of adventure, independence, and courage. She is widely held as a feminist icon and an inspiration to women everywhere for the conviction with which she pursued her own goals and career rather than giving in to the current view of women as less-capable than men. P age |7 Christopher Columbus (1401 - 1506) â€Å"I should not proceed by land to the East, as is customary, but by a Westerly route, in

Saturday, December 14, 2019

Isolation of Single Human Hematopoietic Stem Cells Capable Free Essays

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment A variety of distinct progenitors arising from self-renewing hematopoietic stem cells (HSCs) allow for the production of mature blood cell lineages. Human HSCs are poorly understood due to their rarity and difficulty to segregate them from multipotent progenitors (MPPS) to obtain a pure population for analysis. This study investigates the determining factors of HSCs. We will write a custom essay sample on Isolation of Single Human Hematopoietic Stem Cells Capable or any similar topic only for you Order Now It appears that the majority of HSCs are CD34+, as hown by transplantation and xenograft repopulation assays, however most of these cells are lineage-restricted progenitors and HSCs are therefore rare. Enrichment of HSCs seems reliant on CD45RA, Thyl and CD38 expression. Further study into the role of each of these factors in HSC differentiation is required. In this study a range of assays were carried out in an attempt to identify and separate HSCs from MPPs. Recently it was shown that a depletion in Thyl expression in the CD34+CD38-CD45RA- compartment of lineage-depleted cord blood was ufficient to separate HSCs from MPPs. However, further studies gave rise to concern surrounding this theory. They then used an optimized HSC xenograft assay and flow- sorted cord blood HSCs and MPPs into functionally characterized fractions. Data obtained from this assay suggested that cells with extensive self-renewal potential exist in both Thyl+ and Thyl- subsets. However, more extensive research was required to investigate the disparity in secondary transfer efficiency between subsets. To distinguish the cause of such disparity the Thyl subsets were sorted into Thyl+ and Thy- cells and cultured with stroma cells known to express HSC supportive ligands. The results demonstrated that the Thyl- compartment is heterogeneous and contains a small fraction with repopulating activity and a larger fraction with MMP- like activity and therefore may account for the differences in efficiency between subsets. To further distinguish HSCs in both Thy+ and Thy- subsets they analysed cell surface markers and found only CD49f to be differentially expressed between subsets. Next they investigated whether HSCs could be identified using CD49f expression. Data recovered indicated that human HSCs are indeed marked by CD49f. Further tests were carried out on Thyl-CD49f+ and Thyl-CD49f- subsets. Results revealed Thyl-CD49f- cells are short term HSCs as they fail to engraft long-term, indicating that these are MPPs. Investigation into the role of mitochondrial dye rhodamine-123 (Rho) in HSC enrichment. Results indicated twofold enrichment for HSCs compared to Thyl+ alone as opposed to Thyl +Rholo. The next aspect nvestigated was whether the addition of Rho to Thyl +CD49f+ would permit robust engraftment of single human HSCs. This investigation was carried out using single cell transplantation with two separate experiments focusing on engraftment and Thyl +RholoCD49f+ cells provides evidence that human HSCs express CD49f. These findings illustrated by Notta et al. will aid in identifying gene regulatory networks that govern human HSC function and therefore allow manipulation of human HSCs ex vivo with the aim of overcoming the barriers associated with transplantation. How to cite Isolation of Single Human Hematopoietic Stem Cells Capable, Papers